School of Food Science and Nutrition

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Michael Zulyniak

Lecturer in Obesity
Research section: Nutrition and Public Health

Contact details

Room: E7.67
Tel: +44 (0)113 3430685
Email: M.A.Zulyniak@leeds.ac.uk

Keywords

nutrition
health
ethnicity
genomics
epidemiology
obesity
diabetes
cardiovascular disease

Photograph of Michael Zulyniak

Research interests

Currently, and through my academic research, I work alongside fantastic and established leaders in the fields of nutrition, genomics (i.e., gene expression, methylation, lipidomics), epidemiology, physical activity, and physiology and evaluate their contribution towards the development and prevention of obesity, type-2 diabetes, and cardiovascular disease. With particular focus on how and why responses to treatment differs between populations. To continue down this road and aimed at understanding how these systems work together and contribute toward health and disease, my research interests cover four primary areas:

  1. The interaction between the human genome and nutrition and its role in health and risk of disease;
  2. The interaction between physical activity and nutrition and its impact on health and risk of disease;
  3. Identifying and understanding these interactions at the population level (ethnicity, sex, age, etc.) in order to tailor treatment options and improve current health practices (diet and exercise);
  4. Barriers and facilitators in the home and family environment that impact adherence to common health practices in order to tailor the treatments and improve their feasibility and fidelity; and
  5. Summary of research evidence (through systematic reviews and meta-analyses).

Education

  • BSc. University of Saskatchewan (Canada), Kinesiology
  • MSc. University of Aberdeen (UK) Molecular Exercise Physiology
  • PhD. University of Guelph (Canada), Human Health and Nutritional Sciences
  • Research Fellowship. McMaster University (Canada). Department of Medicine.

Research Funding

  • World Health Organization. Systematic review and meta-analysis on the effects of dietary PUFA on cardiometabolic, atopic, and neurocognitive development in children, pregnant women, and adults. Co-PI with RJ de Souza. 26,358
  • Hamilton Health Sciences. New Investigator Fund. Trimethylamine-N-Oxide (TMAO) and Myocardial Infarction in Multi-Ethnic Canadian and Global Populations 28,200
  • Canadian Institute for Health Research. Randomized Controlled Trials Mentoring Fellowship: Nutrition, Metabolism and Diabetes. 98,077

Publications

Anand SS, Gupta M, Teo KK, Schulze KM, Desai D, Abdalla N, Zulyniak M, de Souza R, Wahi G, Shaikh M, Beyene J, de Villa E, Morrison K, McDonald SD, Gerstein H, South Asian Birth Cohort (START) - Canada Investig Causes and consequences of gestational diabetes in South Asians living in Canada: results from a prospective cohort study. CMAJ Open 5 E604-E611, 2017
DOI:10.9778/cmajo.20170027
View abstract

Bell KE, Snijders T, Zulyniak M, Kumbhare D, Parise G, Chabowski A, Phillips SM A whey protein-based multi-ingredient nutritional supplement stimulates gains in lean body mass and strength in healthy older men: A randomized controlled trial PLoS ONE 12 -, 2017
DOI:10.1371/journal.pone.0181387
View abstract

Stearns JC, Zulyniak MA, de Souza RJ, Campbell NC, Fontes M, Shaikh M, Sears MR, Becker AB, Mandhane PJ, Subbarao P, Turvey SE, Gupta M, Beyene J, Surette MG, Anand SS Ethnic and diet-related differences in the healthy infant microbiome Genome Medicine 9 -, 2017
DOI:10.1186/s13073-017-0421-5
View abstract

Zulyniak MA, de Souza RJ, Mente A, Kandasamy S, Nundy M, Desai D, Raman K, Hasso R, Pare G, Beyene J, Anand SS A randomized controlled trial of the effects of a prudent diet on cardiovascular risk factors, gene expression, and DNA methylation - the Diet and Genetic Intervention (DIGEST) Pilot study BMC Nutrition 2 -, 2016
DOI:10.1186/s40795-016-0074-6
View abstract

Zulyniak MA, Roke K, Gerling C, Logan SL, Spriet LL, Mutch DM Fish oil regulates blood fatty acid composition and oxylipin levels in healthy humans: A comparison of young and older men Molecular Nutrition and Food Research 60 631-641, 2016
DOI:10.1002/mnfr.201500830
View abstract

de Souza RJ, Zulyniak MA, Desai D, Shaikh MR, Campbell NC, Lefebvre DL, Gupta M, Wilson J, Wahi G, Atkinson SA, Teo KK, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR, Anand SS, Beyene J, Denburg JA, McDonald S, Mente A, Meyre D, Morrison K, Pare G, Surette M Harmonization of food-frequency questionnaires and dietary pattern analysis in 4 ethnically diverse birth cohorts Journal of Nutrition 146 2343-2350, 2016
DOI:10.3945/jn.116.236729
View abstract

Anand SS, Hawkes C, de Souza RJ, Mente A, Dehghan M, Nugent R, Zulyniak MA, Weis T, Bernstein AM, Krauss RM, Kromhout D, Jenkins DJA, Malik V, Martinez-Gonzalez MA, Mozaffarian D, Yusuf S, Willett WC, Popkin BM Food Consumption and its Impact on Cardiovascular Disease: Importance of Solutions Focused on the Globalized Food System Journal of the American College of Cardiology 66 1590-1614, 2015
DOI:10.1016/j.jacc.2015.07.050

Badoud F, Lam KP, Perreault M, Zulyniak MA, Britz-McKibbin P, Mutch DM Metabolomics Reveals Metabolically Healthy and Unhealthy Obese Individuals Differ in their Response to a Caloric Challenge PLOS ONE 10 e0134613-e0134613, 2015
DOI:10.1371/journal.pone.0134613

Badoud F, Perreault M, Zulyniak MA, Mutch DM Molecular insights into the role of white adipose tissue in metabolically unhealthy normal weight and metabolically healthy obese individuals The FASEB Journal 29 748-758, 2015
DOI:10.1096/fj.14-263913

Zulyniak MA Serum fatty acid profiling within distinct lipid fractions provides a more robust indicator of insulin resistance in humans than total triglyceride and fatty acid profiles Applied Physiology, Nutrition, and Metabolism 39 1182-1182, 2014
DOI:10.1139/apnm-2014-0136

Badoud F, Lam KP, DiBattista A, Perreault M, Zulyniak MA, Cattrysse B, Stephenson S, Britz-McKibbin P, Mutch DM Serum and Adipose Tissue Amino Acid Homeostasis in the Metabolically Healthy Obese Journal of Proteome Research 13 3455-3466, 2014
DOI:10.1021/pr500416v

Perreault M, Zulyniak MA, Badoud F, Stephenson S, Badawi A, Buchholz A, Mutch DM A Distinct Fatty Acid Profile Underlies the Reduced Inflammatory State of Metabolically Healthy Obese Individuals PLoS ONE 9 e88539-e88539, 2014
DOI:10.1371/journal.pone.0088539

Zulyniak MA, Perreault M, Gerling C, Spriet LL, Mutch DM Fish oil supplementation alters circulating eicosanoid concentrations in young healthy men Metabolism 62 1107-1113, 2013
DOI:10.1016/j.metabol.2013.02.004

Ralston JC, Zulyniak MA, Nielsen DE, Clarke S, Badawi A, El-Sohemy A, Ma DWL, Mutch DM Ethnic- and sex-specific associations between plasma fatty acids and markers of insulin resistance in healthy young adults Nutrition&Metabolism 10 42-42, 2013
DOI:10.1186/1743-7075-10-42

Zulyniak MA, Ralston JC, Tucker AJ, MacKay KA, Hillyer LM, McNicholas PD, Graham TE, Robinson LE, Duncan AM, Ma DWL, Mutch DM Vaccenic acid in serum triglycerides is associated with markers of insulin resistance in men Applied Physiology, Nutrition, and Metabolism 37 1003-1007, 2012
DOI:10.1139/h2012-081

A. Zulyniak M, M. Mutch D Harnessing Metabolomics for Nutrition Research Current Pharmaceutical Biotechnology 12 1005-1015, 2011
DOI:10.2174/138920111795909113

Zulyniak MA, Ralston JC, Tucker AJ, MacKay KA, Hillyer L, McNicholas PD, Graham TE, Robinson LE, Duncan AM, Ma DWL, Mutch DM The relationship between plasma fatty acids and risk factors for insulin resistance in men Canadian Journal of Diabetes 35 206-207, 2011
DOI:10.1016/S1499-2671(11)52249-X